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Only need to practice for 20 to 30 hours

You will get to know the valuable exam tips and the latest question types in our SEND certification training files, and there are special explanations for some difficult questions, which can help you to have a better understanding of the difficult questions. All of the questions we listed in our SEND practice exam materials are the key points for the IT exam, and there is no doubt that you can practice all of SEND best questions within 20 to 30 hours, even though the time you spend on it is very short, however the contents you have practiced are the quintessence for the IT exam. And of course, if you still have any misgivings, you can practice our SEND certification training files again and again, which may help you to get the highest score in the IT exam.

MRCPUK Endocrinology and Diabetes (Specialty Certificate Examination) Sample Questions:

1. A 61-year-old woman was referred to the blood pressure clinic because of refractory hypertension. One year previously, her blood pressure, urea and electrolytes had been normal. Her current therapy included verapamil modified-release 240 mg daily and doxazosin 16 mg daily.
On examination, she was 1.63 m tall and weighed 90 kg with an elevated waist to hip ratio. Her blood pressure was 182/94 mmHg supine.
Investigations:
serum sodium137 mmol/L (137-144)
serum potassium2.8 mmol/L (3.5-4.9)
serum creatinine79 umol/L (60-110)
plasma renin activity (after 30 min supine)<1.1 pmol/mL/h (1.1-2.7)
plasma aldosterone (after 30 min supine)<135 pmol/L (135-400)
What is the most appropriate investigation?

A) overnight dexamethasone suppression test
B) repeat renin and aldosterone concentrations after stopping verapamil for 2 weeks
C) 24-h urinary electrolytes
D) 24-h urine to assess free cortisol:cortisone ratio
E) analysis of the SCNN1B and SCNN1G genes

2. A 25-year-old woman with type 1 diabetes mellitus presented with light-headedness, nausea, thirst and vomiting of 3 days' duration. She was fully conscious.
On examination, her pulse was 104 beats per minute and her blood pressure was 104/64 mmHg. Urinalysis showed glucose 2+, ketones 3+.
Investigations:
serum sodium150 mmol/L (137-144)
serum potassium5.5 mmol/L (3.5-4.9)
serum chloride105 mmol/L (95-107)
serum urea5.0 mmol/L (2.5-7.0)
serum creatinine90 umol/L (60-110)
random plasma glucose20.0 mmol/L
arterial blood gases, breathing air:
PO212.4 kPa (11.3-12.6)
PCO23.4 kPa (4.7-6.0)
pH7.15 (7.35-7.45)
H+70 nmol/L (35-45)
bicarbonate6 mmol/L (21-29)
What intravenous fluid should be given over the first 30 minutes?

A) compound sodium lactate
B) sodium chloride 0.9%
C) colloid solution
D) sodium chloride 0.18% and glucose 4%
E) sodium chloride 0.45%

3. A 16-year-old boy was referred to the diabetes clinic following the discovery of a random plasma glucose concentration of 18.0 mmol/L. His general practitioner had begun treatment with metformin. The patient had a body mass index of 35 kg/m2 (18-25). He had had problems throughout his childhood, and had been taken out of school and was educated at home by his mother. He was attending the ophthalmology clinic for visual problems.
On examination, he was obese. He had hearing aids in both ears and evidence of acanthosis nigricans. Neither parent had a history of diabetes mellitus.
What is the most likely diagnosis?

A) mitochondrial diabetes
B) type 2 diabetes mellitus
C) Bardet-Biedl syndrome
D) Alstrom's syndrome
E) hepatocyte nuclear factor 1? mutation

4. A 58-year-old man presented with tiredness and breathlessness. He had been treated for type 2 diabetes mellitus and hypertension for the past 10 years. He was free of complications. His current medication included ramipril 10 mg daily, rosuvastatin 10 mg daily, metformin 500 mg three times daily, dapagliflozin 10 mg once daily and exenatide 10 micrograms twice daily.
On examination, his body mass index was 36 kg/m2 (18-25).
Investigations:
haemoglobin93 g/L (130-180)
MCV110 fL (80-96)
white cell count3.6 ? 109/L (4.0-11.0)
platelet count140 ? 109/L (150-400)
reticulocyte count0.5% (0.5-2.4)
serum ferritin250 ug/L (15-300)
serum vitamin B1240 ng/L (160-760)
serum folate3.0 ug/L (2.0-11.0)
Which medication is most likely to be contributing to his anaemia?

A) exenatide
B) dapagliflozin
C) rosuvastatin
D) metformin
E) ramipril

5. A 39-year-old man was admitted with severe burns.
On examination, he was noted to be persistently tachycardic.
Investigations:
serum thyroid-stimulating hormone0.2 mU/L (0.4-5.0)
serum free T410.0 pmol/L (10.0-22.0)
serum free T32.5 pmol/L (3.0-7.0)
What is the most appropriate next step in investigation of his thyroid status?

A) radionuclide thyroid uptake scan
B) repeat blood tests after recovery
C) thyroid autoantibodies
D) reverse tri-iodothyronine
E) thyrotrophin-releasing hormone test

Solutions: