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Only need to practice for 20 to 30 hours

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American Society of Microbiology ABMM Sample Questions:

1. A patient undergoing chemotherapy for leukemia develops a severe pneumonia. Bronchoalveolar lavage fluid is examined, revealing numerous cysts containing crescent-shaped structures upon silver staining. The patient's CD4+ T-cell count is significantly low. The MOST likely diagnosis is infection with:

A) Pneumocystis jirovecii
B) Histoplasma capsulatum
C) Coccidioides immitis
D) Blastomyces dermatitidis

2. Clavulanic acid is often combined with amoxicillin (e.g., Augmentin™) to overcome certain types of bacterial resistance. What is the primary mechanism by which clavulanic acid enhances amoxicillin's activity?

A) It functions as a potent, irreversible inhibitor of many bacterial beta-lactamase enzymes.
B) It increases the outer membrane permeability to amoxicillin in Gram-negative bacteria.
C) It binds to alternative penicillin-binding proteins (PBPs), providing a synergistic bactericidal effect.
D) It inhibits bacterial efflux pumps that would otherwise remove amoxicillin from the cell.

3. An elderly patient in a long-term care facility develops a localized outbreak of painful vesicles along a dermatome. Tzanck smear of a vesicle reveals multinucleated giant cells. The MOST likelycausative agent is:

A) Varicella-zoster virus
B) Orf virus
C) Herpes simplex virus type 1
D) Coxsackievirus

4. A patient with HIV infection and a very low CD4+ T-cell count develops a disseminated infection with a fungus that is commonly found in pigeon droppings. The MOST likely causative agent is:

A) Saccharomyces cerevisiae
B) Candida glabrata
C) Cryptococcus neoformans
D) Cryptococcus gattii

5. Which virus is recognized as the leading cause of sporadic, severe gastroenteritis in infants and young children globally, for which effective vaccines are now available?

A) Astrovirus
B) Norovirus
C) Enteric Adenovirus (serotypes 40, 41)
D) Rotavirus

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