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American Society of Microbiology ABMM real answers - ABMM

ABMM
  • Exam Code: ABMM
  • Exam Name: ABMM
  • Updated: Nov 09, 2025
  • Q & A: 204 Questions and Answers
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American Society of Microbiology ABMM Sample Questions:

1. A research laboratory is investigating the quorum sensing system in Pseudomonas aeruginosa. They identify a novel autoinducer molecule and a corresponding transcriptional regulator. Disruption of the gene encoding this regulator leads to a significant decrease in the production of virulence factors such as elastase and pyocyanin. Further analysis reveals that this regulator directly binds to the promoter regions of these virulence genes in the presence of the autoinducer. This regulatory mechanism is an example of:

A) A global regulatory network controlled by alternative sigma factors.
B) A two-component regulatory system involving a sensor kinase and a response regulator.
C) A post-transcriptional regulatory mechanism involving small regulatory RNAs.
D) A direct transcriptional activation mechanism dependent on a small signaling molecule.


2. A clinical microbiology laboratory is implementing whole-genome sequencing (WGS) for enhanced surveillance of Listeria monocytogenes isolates associated with foodborne outbreaks. WGS provides several advantages over traditional subtyping methods like pulsed-field gel electrophoresis (PFGE). Which of the following is the MOST significant advantage of WGS in this context?

A) Faster turnaround time for obtaining results.
B) Lower cost per isolate compared to PFGE.
C) Higher discriminatory power for resolving phylogenetic relationships and identifying outbreakclusters.
D) Easier standardization and inter-laboratory comparison of data.


3. Caspofungin, micafungin, and anidulafungin belong to the echinocandin class of antifungal agents. Their primary mechanism of action involves the non-competitive inhibition of:

A) Nucleic acid synthesis via thymidylate synthase
B) Fungal protein synthesis via ribosomal binding
C) Fungal cell wall synthesis via (1#3)-#-D-glucan synthase
D) Ergosterol synthesis via lanosterol demethylase


4. During an investigation of a foodborne outbreak linked to a church supper, 80 people ate the suspected chicken dish, and 32 subsequently developed gastroenteritis. Among 50 people who did not eat the chicken dish, 5 developed similar symptoms. What is the attack rate among those who ate the chicken dish?

A) 40%
B) 10%
C) 64%
D) 5%


5. An immunocompromised patient returning from a trip to the southwestern United States presents with fever, cough, and chest pain. Chest X-ray shows diffuse pulmonary infiltrates. Sputum culture grows a dimorphic fungus that forms spherules containing endospores at 37°C. The MOST likely causative agent is:

A) Histoplasma capsulatum
B) Coccidioides immitis
C) Paracoccidioides brasiliensis
D) Blastomyces dermatitidis


Solutions:

Question # 1
Answer: D
Question # 2
Answer: C
Question # 3
Answer: C
Question # 4
Answer: A
Question # 5
Answer: B

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