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ASCP MEDICAL LABORATORY TECHNICIAN - MLT(ASCP) Sample Questions:

1. In sickle cell anemia, rapid hemoglobin turnover may be present. HbA1C and other glycated hemoglobin assays are not valid in rapid hemoglobin turnover and in abnormal hemoglobin conditions. Fructosamine measurements can be used because of shorter half life of albumin.
HbA1C measurements are NOT ordinarily used to monitor long-term diabetic control in a diabetic with sickle cell anemia.

A) false
B) true

2. The end of the initial phase of HH treatment is considered when the serum ferritin decreases to between 20 and
50 ng/mL.
What is a typical finding for determining the endpoint for the initial or iron-depletion phase of treatment for hereditary hemochromatosis (HH)?

A) The transferrin saturation drops below 20%
B) The hepatic iron index returns to normal
C) The serum iron falls to below 35 g/dL.
D) The serum ferritin decreases to between 20 and 50 ng/mL

3. May-Hegglin anomaly is a rare autosomal dominant condition in which patients are at risk for bleeding and infections. It is characterized by the presence of large Dohle body like inclusions within neutrophils, eosinophils, basophils, and monocytes.
The WBC anomaly indicated by the arrow in this illustration is:

A) Pelger-Huet anomaly
B) May-Hegglin anomaly
C) Alder-Reilly anomaly
D) Toxic granulation

4. A positive spot test shows agglutination of horse erythrocytes when added to patient serum previously absorbed with guinea pig kidney, but not when added to patient serum previously absorbed with beef erythrocyte stroma. The test is generally simple, sensitive, and specific, but false negative are common in young children with mononucleosis.
The most common rapid slide test (MONOSPOT©) for infectious mononucleosis employs:

A) Sheep erythrocytes
B) Horse erythrocytes
C) None of the above
D) Intact beef erythrocytes

5. Which area of the laboratory is responsible for blood coagulation studies that test for the patient's ability to clot their blood?

A) Clinical chemistry
B) Hematology
C) Blood banking/transfusion medicine
D) Immunology

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