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BPS Pharmacotherapy (Part1 and Part2) Sample Questions:

1. A 72-year-old woman with a long history of schizophrenia has been admitted to the state hospital because of a recent relapse while on risperidone 5 mg daily. It is decided to use an equivalent dose of ziprasidone. Which reference would most likely provide this information?

A) Diagnostic and Statistical Manual of Mental Disorders - V
B) The Sanford Guide
C) Drug Facts & Comparisons
D) Martindale: The Complete Drug Reference

2. A 40-year-old transplant recipient who is receiving cyclosporine develops seizures requiring anticonvulsant therapy. Because a drug interaction is likely to occur between cyclosporine and phenytoin, the pharmacotherapy specialist suggests that the resident do which of the following?

A) Decrease the cyclosporine dose.
B) Increase the phenytoin dose.
C) Increase the cyclosporine dose.
D) Decrease the phenytoin dose.

3. A 69-year-old Woman with chronic liver disease treated with furosemide and potassium chloride for ascites and peripheral edema presents with weakness and fatigue. Her serum laboratory Values are:
* Sodium: 138 mEq/L
* Potassium: 2.6 mEq/L
* Glucose: 88 mg/dL
* BUN: 33 mg/dL
* Chloride: 101 mEq/L
* HCO3- 26 mEq/L
* Creatinine: 1.1 mg/dL
Attempts to increase her serum potassium over the next 48 hours include intravenous replacement (240 mEq over this period), without success. The current serum potassium concentration is 2.8 mEq/L. Which of the following is the most appropriate test to obtain for this patient?

A) Urinary potassium
B) Serum magnesium
C) Urinary sodium
D) Serum antidiuretic hormone

4. A nurse administering an injectable narcotic is stuck with the needle. Which of the following is the most important information about the nurse's immune status to determine appropriate bloodborne pathogen/hepatitis B procedures?

A) Date of last dose of hepatitis B immune globulin
B) Current hepatitis B surface antigen (HBsAg) status
C) Dates of last hepatitis B vaccination
D) Current hepatitis B surface antibody (anti-HBs) status

5. A study compared treatment with cinacalcet versus treatment with placebo in subjects with known hyperparathyroidism. The primary outcome of the study was the proportion of study subjects with a mean intact parathyroid hormone level < 250 pg/mL. Among the cinacalcet group (n = 371), 43% of subjects achieved the primary outcome; among the placebo group (n =
370), 5% achieved the primary outcome (p<0.05).
Which of the following is the number needed to treat (NNT)?

A) 1
B) 14
C) 8
D) 3

Solutions: